N-Arylpiperazinyl-N'-propylamino Derivatives of Heteroaryl Amides as Functional Uroselective α1-Adrenoceptor Antagonists

TR Elworthy, APDW Ford, GW Bantle…

文献索引：Journal of Medicinal Chemistry, , vol. 40, # 17 p. 2674 - 2687

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被引用次数: 52

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The initial aryl amides of interest were produced from 2-aminonicotinonitrile 10 by either a Ritter (9) or controlled hydrolysis (primary carboxamide, 11) reactions. As outlined ...