Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist. alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

…, E Nielsen, P Krogsgaard-Larsen

文献索引：Hansen; Lauridsen; Nielsen; Krogsgaard Larsen Journal of Medicinal Chemistry, 1983 , vol. 26, # 6 p. 901 - 903

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被引用次数: 38

摘要

The enantiomers of the glutamic acid central nervous system receptor agonist a-amino-3- hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) were prepared via kinetic resolution of the racemic N-acetylated 3-methoxy derivative by reusable, immobilized aminoacylase. L- ...