Cs 2 CO 3 in pyrrolidinone promoted hydration of functionalized (hetero) aryl nitriles under metal-free conditions

S Sahnoun, S Messaoudi, JF Peyrat, JD Brion…

文献索引：Sahnoun, Sophian; Messaoudi, Samir; Peyrat, Jean-Francois; Brion, Jean-Daniel; Alami, Mouad Tetrahedron Letters, 2012 , vol. 53, # 23 p. 2860 - 2863

全文：HTML全文

被引用次数: 11

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... An efficient hydration reaction of various (hetero)aryl nitriles using Cs 2 CO 3 in pyrrolidinone is described. This new metal-free protocol proved to be highly effective and general to synthesize a variety of (hetero)aryl amides. ... Various (hetero)aryl amides were efficiently prepared ...