Substituted ω-(4-oxo-3, 4-dihydro-5-pyrimidinyl) alkanoic acids, their derivatives and analogues

…, A Černý, J Křepelka, J Vachek

文献索引：Beran; Cerny; Krepelka; Vachek Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 1 p. 292 - 298

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被引用次数: 10

摘要

Abstract Condensation of guanidine with diethyl 2-formylbutanedioate (XI), diethyl 2- cyanobutanedioate (XII), diethyl 2-cyanoheptanedioate (XIII), ethyl 6, 6-dicyanohexanoate (XIV), or diethyl 6, 6-dicyanoundecanedioate (XV), followed by hydrolysis of the esters formed, afforded the respective substituted ω-(2-amino-5-pyrimidinyl) alkanoic acids (II, V, VI, IX and X). Analogously, condensation of the ester XIII with urea or thiourea gave acids ...