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Organic letters

Regioselective Synthesis of N-β-Hydroxyethylaziridines by the Ring-Opening Reaction of Epoxides with Aziridine Generated in Situ

HY Kim, A Talukdar, M Cushman

文献索引:Kim, Ha Young; Talukdar, Arindam; Cushman, Mark Organic Letters, 2006 , vol. 8, # 6 p. 1085 - 1087

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被引用次数: 14

摘要

Biologically important N-β-hydroxyethylaziridine intermediates were conveniently prepared by regioselective ring-opening reactions of diversely substituted epoxides. Ethyleneimine generated in situ under basic conditions from β-chloroethylamine was used as a ...