The Journal of Organic Chemistry

Potential Carcinostatic Derivatives of Benzo [a]-and Benzo [b] phenoxazine

K SEN, DA SHIRLEY

文献索引：Sen,K.; Shirley,D.A. Journal of Organic Chemistry, 1961 , vol. 26, p. 3861 - 3863

全文：HTML全文

被引用次数: 3

摘要

It has been demonstrated that a number of ben-zo~ a] phenoxazonium salts related to Kile Blue dyes possess tumor growth retarding action in mice as well as antituberculous action in mice. 3 We have synthesized for evaluation as potential cancer chemotherapeutic agents some N-dialkylaminoalkyl and N-his@-chloroethy1) aminoethyl derivatives of benzo [a] phenoxazine (I) and benzo [b]-phenoxazine (11). The so-called “nitrogen mustard” types ( ...