Tetrahedron letters

Simple synthesis of 4-thiothymidine, 4-thiouridine and 6-thio-2′-deoxyguanosine

YZ Xu, Q Zheng, PF Swann

文献索引：Xu, Yao-Zhong; Zheng, Qinguo; Swann, Peter F. Tetrahedron Letters, 1991 , vol. 32, # 24 p. 2817 - 2820

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被引用次数: 29

摘要

Abstract 4-triazolo-pyrimidine nucleosides and 6-O-(mesitylenesulfonyl)-2′- deoxyguanosine, when treated with thiolacetic acid at room temperature, gave the corresponding 4-thiopyrimidine nucleosides and 6-thio-2′-deoxyguanosine with high yields (86–93%). Possible mechanisms are discussed.