Tetrahedron

Iodine: A versatile reagent in carbohydrate chemistry IV. Per-O-acetylation, regioselective acylation and acetolysis

KPR Kartha, RA Field

文献索引：Kartha, K. P. Ravindranathan; Field, Robert A. Tetrahedron, 1997 , vol. 53, # 34 p. 11753 - 11766

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被引用次数: 166

摘要

Iodine has been found to be an effective Lewis acid for promoting the per-O-acetylation of unprotected sugars. Under controlled conditions it can bring about regioselective acylation of carbohydrate derivatives. At higher concentration and with longer reaction times, iodine can effect the selective acetolysis of benzyl ether-protected primary hydroxyl groups. All of these reactions proceed in high yield, are easy to carry out and make use of readily ...