Procedures are described for the o-chlorination of tetrachloro-o-xylene, for the w- bromination of tetrachloro-o-xylene, tetrachloro-p-xylene, and trichloromesitylene and for replacement of the bromine by hydroxyl (via the acetates), by carboxymethyl (via malonic ester alkylation), by phenyl (via the Friedel-Crafts reaction), and by n-propoxy (via reaction with sodium propoxide in n-propyl alcohol).
![[2,3,4,5-tetrachloro-6-(hydroxymethyl)phenyl]methanol结构式](https://image.chemsrc.com/caspic/482/56135-96-7.png)