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Bioorganic & medicinal chemistry letters

Synthesis and activities of naphthalimide azoles as a new type of antibacterial and antifungal agents

YY Zhang, CH Zhou

文献索引:Zhang, Yi-Yi; Zhou, Cheng-He Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4349 - 4352

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被引用次数: 59

摘要

Abstract Naphthalimide-derived azoles as a new type of antimicrobial agents were synthesized and evaluated for their efficiency in vitro against eight bacteria and two fungi by two fold serial dilution technique. Most title compounds exhibited good antimicrobial potency with low MIC values ranging from 1 to 16 μg/mL. Notably, some synthesized compounds displayed comparable or even better antibacterial and antifungal activities against some ...