N-Tosyloxycarbamates as a source of metal nitrenes: rhodium-catalyzed CH insertion and aziridination reactions

H Lebel, K Huard, S Lectard

文献索引：Lebel, Helene; Huard, Kim; Lectard, Sylvain Journal of the American Chemical Society, 2005 , vol. 127, # 41 p. 14198 - 14199

全文：HTML全文

被引用次数: 182

摘要

The rhodium-catalyzed decomposition of N-tosyloxycarbamates to generate metal nitrenes which undergo intramolecular CH insertion or aziridination reaction is described. Aliphatic N- tosyloxycarbamates produce oxazolidinones with high yields and stereospecificity through insertion in benzylic, tertiary, and secondary CH bonds. Intramolecular aziridination occurs with allylic N-tosyloxycarbamates to produce aziridines as single diastereomers. The ...