Asymmetric synthesis catalyzed by chiral ferrocenylphosphine-transition-metal complexes. 8. Palladium-catalyzed asymmetric allylic amination

T Hayashi, A Yamamoto, Y Ito, E Nishioka…

文献索引：Hayashi, Tamio; Yamamoto, Akihiro; Ito, Yoshihiko; Nishioka, Eriko; Miura, Hitoshi; Yanagi, Kazunori Journal of the American Chemical Society, 1989 , vol. 111, # 16 p. 6301 - 6311

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被引用次数: 338

摘要

Abstract: Chiral ferrocenylphosphine ligands, represented by (R)-N-methyl-N-[bis (hydroxymethyl) methyl]- 1-[(S)-1', 2-bis-(diphenylphosphino) ferrocenyl] ethylamine ((I?)-(.!+ la), which have a pendant side chain bearing a hydroxy group at the terminal position, were designed and used successfully for palladium-catalyzed asymmetric allylic amination of allylic substrates containing a 1, 3-disubstituted propenyl structure (RCH= CHCH (X) R: R ...