Benzoylurea derivatives as a novel class of antimitotic agents: synthesis, anticancer activity, and structure− activity relationships

DQ Song, Y Wang, LZ Wu, P Yang…

文献索引：Okada; Koyanagi; Yamada; Haga Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2308 - 2315

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被引用次数: 22

摘要

... 14b inhibited human hepatocarcinoma by 86% in volume in nude mice. ... cancer chemotherapy.( 7) Therefore, searching for drugable small tubulin ligands with novel chemical structures or ... modes of action has become an active field of investigation in medicinal chemistry.(8, 9 ...