Ruthenium tetroxide oxidation of N, C-protected derivatives of L-2, 4-diaminobutyric acid, L- ornithine and L-lysine was carried out under two-phase conditions and the corresponding imides, formed through the oxidation of the methylene adjacent to the ω-amino group, were obtained in good yields. Removal of the protecting groups from the products gave L- asparagine, L-glutamine and L-2-aminoadipic acid 6-amide, respectively. Thus, the first ...
