Synthesis of 4??methylthio??2 (1H)??pyridone derivatives using ketene dithioacetals

Y Tominaga, M Kawabe…

文献索引：Tominaga, Yoshinori; Kawabe, Masanori; Hosomi, Akira Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1325 - 1331

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被引用次数: 20

摘要

Abstract Reaction of various active methylene compounds with ketene dithioacetals, bis (methylthio) methylenemalononitrile (1a) and bis (methylthio) methylenecyanoacetamide (1b) gave the corresponding 3-cyano-4-methylthio-2 (1H)-pyridone derivatives. The transformation of 4-methylthio-2-oxo-2H-pyran-3-carbonitrile in-to 4-methylthio-2 (1H)- pyridone derivatives was also described.