Synthesis and electrochemical study of a new chiral tris-catecholamide analogue of enterobactin

N Cheraiti, ME Brik, A Gaudemer, G Kunesh

文献索引：Cheraiti; Brik; Gaudemer; Kunesh Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 5 p. 781 - 786

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被引用次数: 6

摘要

The comparison of siderophore complex redox potentials with those of physiological reductants may aid in the clarification of the mechanism of iron metabolism. In this paper, a new chiral tris-catecholamide compound N, N′, N ″-tris-(2, 3-dihydroxybenzoyl)-1, 1, 1-tris- (L-methioninemehyl)-ethane or H6L (11) has been synthesised in nine steps, and may mimic the release of iron from enterobactin to the agents which are directly involved in cell ...