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A new synthesis of 2-substituted pyridines via aluminum chloride induced heteroarylation of arenes and heteroarenes

M Pal, VR Batchu, I Dager, NK Swamy…

文献索引:Pal, Manojit; Batchu, Venkateswara Rao; Dager, Indu; Swamy, Nalivela Kumara; Padakanti, Srinivas Journal of Organic Chemistry, 2005 , vol. 70, # 6 p. 2376 - 2379

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被引用次数: 27

摘要

We herein report a new synthesis of 2-(hetero) aryl-substituted pyridines via heteroarylation of arenes/heteroarenes through AlCl3-induced CC bond-forming reactions. 2-Halopyridines bearing an electron-withdrawing group were reacted with a number of (hetero) arenes to give 2-aryl/heteroaryl-substituted pyridines in good yields.