Design, synthesis and evaluation of arylidene pyrrolo and pyrido fused quinazolones as antimicrobial agents

K Nepali, R Ojha, A Singh, A Budhiraja…

文献索引：Nepali, Kunal; Ojha, Ritu; Singh, Aninder; Budhiraja, Abhishek; Bedi, Preet Mohinder Singh; Dhar, Kanaya Lal Letters in Drug Design and Discovery, 2013 , vol. 10, # 6 p. 522 - 528

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摘要

Keeping in view the potential of heterocyclic fused quinazolones and arylidene linked heterocycles, hybrid molecules of these functionalities were designed and synthesised. All the synthesised molecules were characterized by spectroscopic techniques and evaluated for antimicrobial activity against 2 Gram positive bacterial strains; Staphylococcus aureus (MTCC 96) and Bacillus subtilis (MTCC 2451), 3 Gram negative bacterial strains; ...