Clean six-step synthesis of a piperidino-thiomorpholine library using polymer-supported reagents

J Habermann, SV Ley, JS Scott

文献索引：Habermann, Joerg; Ley, Steven V.; Scott, James S. Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 19 p. 3127 - 3130

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被引用次数: 58

摘要

The growing speed of biological evaluation of potential drug substances during the past years has imposed the need to develop new methods for the fast and efficient generation of new chemical entities. In general, chemical libraries containing large numbers of compounds may be prepared either on polymer supports or in solution. 1a The use of supported reagents combines the advantages of polymer supported reactions (eg ...