A stereoselective synthesis of indole-. beta.-N-glycosides: an application to the synthesis of rebeccamycin

M Gallant, JT Link, SJ Danishefsky

文献索引：Gallant, Michel; Link, James T.; Danishefsky, Samuel J. Journal of Organic Chemistry, 1993 , vol. 58, # 2 p. 343 - 349

全文：HTML全文

被引用次数: 124

摘要

A variety of natural products in which indolocarbazoles are glycosidically joined to various sugars have been described. Several members of this family have a single indole-N- glycosidic bond while others contain two such linkages. Several of the compounds posessing such single N-glycosidic bonds exhibit antitumor activity. The most potent antitumor agent of this group is rebeccamycinl (1) which was isolated in 1985 from an ...