Tetrahedron Letters

Cyclic trimer of 5-(aminomethyl)-2-furancarboxylic acid as a novel synthetic receptor for carboxylate recognition

TK Chakraborty, S Tapadar, SK Kumar

文献索引：Chakraborty, Tushar K; Tapadar, Subhasish; Kiran Kumar Tetrahedron Letters, 2002 , vol. 43, # 7 p. 1317 - 1320

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被引用次数: 38

摘要

A novel 18-membered cyclic oligopeptide 1 based on 5-(aminomethyl)-2-furancarboxylic acid (2), is developed as an excellent receptor for carboxylate binding having an association constant of 8.64× 103 M− 1 for tetrabutylammonium acetate in CD3CN. The synthesis of 1 was achieved by a high-yielding cyclotrimerization reaction of the unfunctionalized furan amino acid 2.