Synthesis of Protein Conjugates of 2-Carboxy-L-Arabinitol 5-Phosphate and 2-Carboxy-L-Ribitol 5-Phosphate

…, D Florentin, A Marquet

文献索引：Gourlaouen, Nelly; Florentin, Dominique; Marquet, Andree Journal of Carbohydrate Chemistry, 1998 , vol. 17, # 8 p. 1219 - 1238

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被引用次数: 2

摘要

Abstract The synthesis of 5-O-[5-(pentanoic acid)]-phosphono-L-erythro-pent-2-ulose 2 was successfully achieved by coupling benzyl 5-hydroxypentanoate 9b and 1-O-benzyl-L-erythro- pent-2-ulose ethane-1, 2-diyl dithioacetal 13 with the enediol pyrophosphate 18. Compound 2 was coupled to carrier proteins, porcine thyroglobuline and bovine serum albumin and the conjugates were treated with KCN to give conjugates of the hapten 1, designed to raise ...