Synthesis of Methyl-1-(tert-butoxycarbonylamino)-2-vinylcyclopropanecarboxylate via a Hofmann Rearrangement Utilizing Trichloroisocyanuric Acid as an Oxidant

…, PJ Nichols, T Sammakia, PJ Stengel

文献索引：Crane, Zackary D.; Nichols, Paul J.; Sammakia, Tarek; Stengel, Peter J. Journal of Organic Chemistry, 2011 , vol. 76, # 1 p. 277 - 280

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被引用次数: 21

摘要

A trichloroisocyanuric acid (TCCA) mediated Hofmann rearrangement was utilized to synthesize methyl-1-(tert-butoxycarbonylamino)-2-vinylcyclopropanecarboxylate. A variety of functional groups are tolerated in this reaction including vinyl, cyclopropyl, pyridyl, aryl, benzyl, and nitro groups.

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