A new synthetic route to 1, 3, 4??oxadiazoles. Pharmacological study of some new derivatives

…, C Davrinche, E Nguyen??Tri??Xuong…

文献索引：Reynaud; El Hamad; Davrinche; Nguyen-Tri-Xuong; Tran; Rinjard Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 4 p. 991 - 993

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被引用次数: 17

摘要

Abstract 2-Substituted 1, 3, 4-oxadiazoles have been examined as possible prodrugs of antidepressant hydrazides. A new method of synthesis of this heterocycle from thionoester and five new oxadiazoles substituted at the 2-position by a 4-pyridyl or 4-aminophenyl group and at the 5-position by a phenyl group are described. Abstract Les auteurs se sont intéréssés anx 1, 3, 4-oxadiazoles substitués en 2 comme d'éventuelles prodrogues d' ...