Tetrahedron

Total synthesis of drimane sesquiterpenes from S-(+)-carvone (part 5)

…, AA Verstegen-Haaksma, BJM Jansen, A de Groot

文献索引：Groot, Aede de; Jansen, Ben J. M. Journal of Organic Chemistry, 1984 , vol. 49, # 11 p. 2034 - 2035

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被引用次数: 14

摘要

Conjugate addition of potassium cyanide to S-(+)-carvone followed by annulation with methyl vinyl ketone nitrile 4 in high yield. Methylation of 4, removal of the isopropenyl group and the introduction of C-12 via formylation then gave the unsaturated keto lactone 21 which