Tetrahedron

Reactions of hydroxylamines with ethyl cyanoformate. preparation of aminonitrones and their synthetic applications.

PS Branco, S Prabhakar, AM Lobo, DJ Williams

文献索引：Branco; Prabhakar; Lobo; Williams Tetrahedron, 1992 , vol. 48, # 30 p. 6335 - 6360

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被引用次数: 40

摘要

The reaction of hydroxylamines with ethyl cyanoformate 1 leads to the formation of carbethoxyamino nitrones 2. UV spectroscopy provided information that suggested the nitrone structure for these compounds in solution. X-ray analysis of 2a confirmed that it exists entirely in the nitrone form in the solid state. These nitrones are shown to be excellent starting materials for a variety of nitrogen containg compounds, namely, imidazoles, ...