An unexpected diethyl azodicarboxylate-promoted dehydrogenation of tertiaryamine and tandem reaction with sulfonyl azide

X Xu, X Li, L Ma, N Ye, B Weng

文献索引：Xu, Xiaoliang; Li, Xiaonian; Ma, Lei; Ye, Ning; Weng, Bojie Journal of the American Chemical Society, 2008 , vol. 130, # 43 p. 14048 - 14049

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被引用次数: 63

摘要

It is shown here for the first time that diethyl azodicarboxylate promotes dehydrogenation of tertiaryamines to afford enamines, which subsequently take place in tandem reactions with sulfonyl azides to give the N-sulfonyl amidine derivatives. A number of different substituted tertiaryamines and sulfonyl azides can successfully be coupled, and several functionalized groups are tolerated in this system. The reaction described here is mild, general, and ...