Chemical Communications

Highly regioselective opening of zirconacyclopentadienes by remote coordination: concise synthesis of the furan core of the leupyrrins

T Debnar, S Dreisigacker, D Menche

文献索引：Debnar, Thomas; Dreisigacker, Sandra; Menche, Dirk Chemical Communications, 2013 , vol. 49, # 7 p. 725 - 727

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被引用次数: 11

摘要

An efficient protocol for the highly regioselective opening of aliphatic zirconacyclopentadienes is reported. The one-pot process involves a zirconocene-mediated cyclization of 1, 6-diynes and highly selective cleavage of the metallacycles with NBS and enables a concise synthesis of the tetrahydrofuran-core of the leupyrrins.