Introduction librium can be shifted in favor of 3 if during the equili-The synthesis of cinnoline derivatives is an area of inter-bration the primary amine formed is consumed (eg by est because of their applications in agricultural, biologi-acetylation [6a, 11] or by formylation [12]) to form N-substical,[1] and medical fields.[2] Derivatives of 1, 2-and 1, 4-di-tuted 1- aminoindoles 4. The normal procedure for carrying hydrocinnolines are particularly ...