4.25; neut. equiv., 164.7. Found: C, 65.33; H, 6.24; N, 4.17; neut. equiv., 162.0. We wish to thank Mr. A. Lanzilotti for tech- nical assistance in this investigation and Miss Edith Sozio for assistance in preparation of the manuscript. Summary 1. A general synthesis of l-arylcyclohexane- carboxylic acids has been described. 2. Certain esters of this general type show pronounced antispasmodic and some analgesic activity. NEWARK, NJ RECEIVED FEBRUARY 8, 1946