Abstract The synthesis of naturally occurring furan derivatives rehmanones A, B, and C is described. Diverse alternative synthetic strategies were developed for the preparation of these natural products. Conjugate addition of a furan to captodative alkene 1-acetylvinyl 4- nitrobenzoate was carried out under Lewis acid catalysis to give the corresponding adduct, which was transformed into rehmanones B and C in three and two steps, respectively. ...
![1,5-bis[5-(methoxymethyl)furan-2-yl]penta-1,4-dien-3-one结构式](https://image.chemsrc.com/caspic/227/850722-50-8.png)
![(1E,4E)-1,5-bis[5-(hydroxymethyl)furan-2-yl]penta-1,4-dien-3-one结构式](https://image.chemsrc.com/caspic/290/1040375-91-4.png)
