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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

2-Phenylindoles. Relationship between structure, estrogen receptor affinity, and mammary tumor inhibiting activity in the rat

E Von Angerer, J Prekajac…

文献索引：Angerer, Erwin von; Prekajac, Jelica; Strohmeier, Josef Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1439 - 1447

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被引用次数: 112

摘要

A number of 2-phenylindole derivatives with one hydroxy group in the meta or para position of the phenyl ring and a second one in position 5, 6, or 7 of the indole nucleus were synthesized. In addition, different alkyl groups were introduced into positions 1 and 3 of the heterocycle. The influence of these structural variations on the binding affinity for the calf uterine estrogen receptor was studied. A prerequisite for the binding is the presence of an ...

间氨基苯甲醚结构式

间氨基苯甲醚

3'-甲氧基苯乙酰溴[用于高效液相色谱标记]结构式

3'-甲氧基苯乙酰溴[用于高效...

~%

6-methoxy-2-(3-methoxyphenyl)-1H-indole结构式

6-methoxy-2-(3-...

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2-bromo-1-(4-methoxyphenyl)butan-1-one结构式

2-bromo-1-(4-me...

对甲氧基苯胺结构式

对甲氧基苯胺

~1%

2-ethyl-5-methoxy-3-(4-methoxyphenyl)-1H-indole结构式

2-ethyl-5-metho...

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5-methoxy-2-(4-methoxyphenyl)indole结构式

5-methoxy-2-(4-...

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2-(4-hydroxyphenyl)-1H-indol-5-ol结构式

2-(4-hydroxyphe...

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对甲氧基苯胺结构式

对甲氧基苯胺

~%

2-(4-hydroxyphenyl)-1H-indol-5-ol结构式

2-(4-hydroxyphe...

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4-甲氧基-α－溴代苯乙酮结构式

4-甲氧基-α－溴代苯乙酮

~%

2-(4-hydroxyphenyl)-1H-indol-5-ol结构式

2-(4-hydroxyphe...

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未登录结构式

~%

1-ethyl-2-(4-hydroxyphenyl)indol-5-ol结构式

1-ethyl-2-(4-hy...

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对甲氧基苯胺结构式

对甲氧基苯胺

~%

1-ethyl-2-(4-hydroxyphenyl)indol-5-ol结构式

1-ethyl-2-(4-hy...

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4-甲氧基-α－溴代苯乙酮结构式

4-甲氧基-α－溴代苯乙酮

~%

1-ethyl-2-(4-hydroxyphenyl)indol-5-ol结构式

1-ethyl-2-(4-hy...

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5-methoxy-2-(4-methoxyphenyl)indole结构式

5-methoxy-2-(4-...

~%

1-ethyl-2-(4-hydroxyphenyl)indol-5-ol结构式

1-ethyl-2-(4-hy...

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6-Methoxy-2-(4-methoxyphenyl)-1-propylindol结构式

6-Methoxy-2-(4-...

~%

2-(4-hydroxyphenyl)-1-propylindol-6-ol结构式

2-(4-hydroxyphe...

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6-methoxy-2-(4-methoxyphenyl)-1H-indole结构式

6-methoxy-2-(4-...

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2-(4-hydroxyphenyl)-1-propylindol-6-ol结构式

2-(4-hydroxyphe...

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间氨基苯甲醚结构式

间氨基苯甲醚

~%

2-(4-hydroxyphenyl)-1-propylindol-6-ol结构式

2-(4-hydroxyphe...

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4-甲氧基-α－溴代苯乙酮结构式

4-甲氧基-α－溴代苯乙酮

~%

2-(4-hydroxyphenyl)-1-propylindol-6-ol结构式

2-(4-hydroxyphe...

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1-ethyl-6-methoxy-2-(4-methoxyphenyl)-3-methyl-1H-indole结构式

1-ethyl-6-metho...

~%

1-ethyl-2-(4-hydroxyphenyl)-3-methylindol-6-ol结构式

1-ethyl-2-(4-hy...

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2-溴-1-(4-甲氧苯基)丙酮结构式

2-溴-1-(4-甲氧苯基)丙酮

~%

1-ethyl-2-(4-hydroxyphenyl)-3-methylindol-6-ol结构式

1-ethyl-2-(4-hy...

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6-methoxy-2-(4-methoxyphenyl)-3-methylindole结构式

6-methoxy-2-(4-...

~%

1-ethyl-2-(4-hydroxyphenyl)-3-methylindol-6-ol结构式

1-ethyl-2-(4-hy...

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间氨基苯甲醚结构式

间氨基苯甲醚

~%

1-ethyl-2-(4-hydroxyphenyl)-3-methylindol-6-ol结构式

1-ethyl-2-(4-hy...

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2-(4-METHOXYPHENYL)-3-METHYL-5-METHOXYINDOLE结构式

2-(4-METHOXYPHE...

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秦哚昔芬结构式

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对甲氧基苯胺结构式

对甲氧基苯胺

~%

秦哚昔芬结构式

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未登录结构式

~%

秦哚昔芬结构式

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乙酸酐结构式

1-ethyl-5-hydroxy-2-(4-hydroxyphenyl)-3-methyl-1H-indol结构式

1-ethyl-5-hydro...

~%

秦哚昔芬结构式

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间氨基苯甲醚结构式

间氨基苯甲醚

4-甲氧基-α－溴代苯乙酮结构式

4-甲氧基-α－溴代苯乙酮

~%

6-methoxy-2-(4-methoxyphenyl)-1H-indole结构式

6-methoxy-2-(4-...

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6-methoxy-2-(4-methoxyphenyl)-1H-indole结构式

6-methoxy-2-(4-...

碘乙烷结构式

~%

1-ethyl-6-methoxy-2-(4-methoxyphenyl)indole结构式

1-ethyl-6-metho...

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间氨基苯甲醚结构式

间氨基苯甲醚

~%

1-ethyl-6-methoxy-2-(4-methoxyphenyl)indole结构式

1-ethyl-6-metho...

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4-甲氧基-α－溴代苯乙酮结构式

4-甲氧基-α－溴代苯乙酮

~%

1-ethyl-6-methoxy-2-(4-methoxyphenyl)indole结构式

1-ethyl-6-metho...

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5-methoxy-2-(4-methoxyphenyl)-1-methyl-1H-indole结构式

5-methoxy-2-(4-...

~%

2-(4-hydroxyphenyl)-1-methylindol-5-ol结构式

2-(4-hydroxyphe...

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5-methoxy-2-(4-methoxyphenyl)indole结构式

5-methoxy-2-(4-...

~%

2-(4-hydroxyphenyl)-1-methylindol-5-ol结构式

2-(4-hydroxyphe...

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对甲氧基苯胺结构式

对甲氧基苯胺

~%

2-(4-hydroxyphenyl)-1-methylindol-5-ol结构式

2-(4-hydroxyphe...

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4-甲氧基-α－溴代苯乙酮结构式

4-甲氧基-α－溴代苯乙酮

~%

2-(4-hydroxyphenyl)-1-methylindol-5-ol结构式

2-(4-hydroxyphe...

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2-溴-1-(4-甲氧苯基)丙酮结构式

2-溴-1-(4-甲氧苯基)丙酮

~%

秦哚昔芬结构式

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5-methoxy-2-(3-methoxyphenyl)-3-methyl-1-propyl-1H-indole结构式

5-methoxy-2-(3-...

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2-(3-hydroxyphenyl)-3-methyl-1-propylindol-5-ol结构式

2-(3-hydroxyphe...

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对甲氧基苯胺结构式

对甲氧基苯胺

~%

2-(3-hydroxyphenyl)-3-methyl-1-propylindol-5-ol结构式

2-(3-hydroxyphe...

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5-methoxy-2-(3-methoxyphenyl)-3-methylindole结构式

5-methoxy-2-(3-...

~%

2-(3-hydroxyphenyl)-3-methyl-1-propylindol-5-ol结构式

2-(3-hydroxyphe...

查看详情