In pursuit of an analogy between fluorine and thioxanthene dioxide, the suitability of the D- TMOC and related functions as base-sensitive amino-protecting groups was examined. Such compounds were found to be cleaved by mild pyridine bases against which the analogous FMOC derivatives are stable. Deblocking gives as a byprodud the methylene sulfone 5 or its adducts with an appropriate secondary deblocking amine. Certain solvents ...
