Tetrahedron letters

New synthesis of 3-substituted indoles using lithium trimethylsilyldiazomethane

T Miyagi, Y Hari, T Aoyama

文献索引：Miyagi, Takashi; Hari, Yoshiyuki; Aoyama, Toyohiko Tetrahedron Letters, 2004 , vol. 45, # 33 p. 6303 - 6305

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被引用次数: 25

摘要

Indoles have a wide spectrum of biological activities. 1 A large number of methods for the construction of the indole nucleus have been reported. 2 Among them, the base- 3a, 3b and 3c or Lewis acid- 3d mediated, and transition-metal-catalyzed 3e, 3f, 3g, 3h and 3i cyclization of o-ethynylaniline derivatives is one of the most useful methods. However, there is still strong demand for new, versatile, and efficient methods for the construction of the indole nucleus.