Palladium-catalyzed hydroamination of 1, 3-dienes: a colorimetric assay and enantioselective additions

O Löber, M Kawatsura, JF Hartwig

文献索引：Loeber; Kawatsura; Hartwig Journal of the American Chemical Society, 2001 , vol. 123, # 18 p. 4366 - 4367

全文：HTML全文

被引用次数: 208

摘要

Mild, selective 1: 1 reactions of amines with dienes to form allylic amines are rare1 and limited to the reaction of cyclic dialkylamines catalyzed by nickel. 2 Late transition metalcatalyzed, amine-induced telomerizations of butadiene1 and oxidative 1, 4 addition of nucleophiles to dienes3 are now well known, and the palladium-catalyzed additions of amines to more reactive eneynes4 and allenes5 have been reported. However, reactions ...