Tetrahedron

Palladium mediated synthesis of isoindolinones and isoquinolinones

MW Khan, AFGM Reza

文献索引：Wahab Khan; Masud Reza Tetrahedron, 2005 , vol. 61, # 47 p. 11204 - 11210

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被引用次数: 32

摘要

The palladium-catalyzed reactions of 2-iodo-N-substituted benzamides with acrylic esters led to N-substituted-3-alkylisoindolinone esters in good yields. The esters of isoindolinones underwent hydrolysis reactions yielding the N-aryl-1, 2, 3, 4-tetrahydro-1-oxoisoquinoline-3- carboxylic acid in good yields.