Tetrahedron

Efficient and selective deprotection method for N-protected 2 (3H)-benzoxazolones and 2 (3H)-benzothiazolones

P Carato, S Yous, D Sellier, JH Poupaert, N Lebegue…

文献索引：Carato, Pascal; Yous, Said; Sellier, Didier; Poupaert, Jacques H.; Lebegue, Nicolas; Berthelot, Pascal Tetrahedron, 2004 , vol. 60, # 45 p. 10321 - 10324

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被引用次数: 20

摘要

Cyclic carbamate flanked with heterocyclic or aliphatic moieties are frequently used in medicinal chemistry. The synthesis of derivatives bearing a free NH often requires the use of a protection method. A literature search reveals very few protection/deprotection methods for cyclic carbamates. In this paper, we described different methods applicable to 2 (3H)- benzoxazolone and 2 (3H)-benzothiazolone.