Medicinal Chemistry Research

Synthesis and antibacterial evaluation of 6-azapyrimidines with α-methylene-γ-(4-substituted phenyl)-γ-butyrolactone pharmacophores

PJ Huang, KH Lee

文献索引：Huang, Po-Jui; Lee, Kuan-Han Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 1081 - 1090

全文：HTML全文

被引用次数: 2

摘要

Abstract A series of 6-substituted 2-[(4-methylene-5-oxo-2-(4-substituted phenyl) tetrahydrofuran-2-yl) methyl]-1, 2, 4-triazine-3, 5 (2 H, 4 H)-diones (5, 6) and 2, 4-bis [(4- methylene-5-oxo-2-(4-substituted phenyl) tetrahydrofuran-2-yl) methyl]-1, 2, 4-triazine-3, 5 (2