Dipyrromethanes have been synthesized using a variety of procedures. 12 For example, the 5-unsubstituted dipyrromethane, has been prepared in three steps from pyrrole. 12a 5-Aryldipyrromethanes have also been synthesized indirectly, requiring either the elimination of a protecting ester group from the pyrrole, 12b or through the formation of a Grignard reagent. 12c A number of other syntheses of dipyrromethanes are based on the direct condensation of carbonyl reagents with ...