Concise Synthesis of Heterocycle-Fused Naphthoquinones by Employing Sonogashira Coupling and Tandem Addition-Elimination/Intramolecular Cyclization

…, M Yamashita, K Sakaguchi, H Tokuda, A Iida

文献索引：Ueda, Kazunori; Yamashita, Mitsuaki; Sakaguchi, Koichi; Tokuda, Harukuni; Iida, Akira Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 6 p. 648 - 654

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被引用次数: 2

摘要

A concise method for the synthesis of heterocycle-fused naphthoquinones such as naphtho [2, 3-b]-furan-4, 9-dione, 1H-benz [f] indole-4, 9-dione, and naphtho [2, 3-b] thiophene-4, 9- dione was developed. This method employed Sonogashira coupling and tandem addition- elimination/intramolecular cyclization, and it enabled the preparation of versatile heterocycle- fused naphthoquinones from one substrate.