Synthesis and structure–activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands

JP Caldwell, JJ Matasi, H Zhang, A Fawzi…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 8 p. 2281 - 2284

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被引用次数: 14

摘要

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... From high-throughput screening of our chemical library, compound 1 was identified as a lead showing moderate affinity for NOP with a K i of 500 nM. ...