前往化源商城

Synthesis and in vitro antiproliferative activity of diphenyl (sulphonylpiperidin-4-yl) methanol derivatives

SBB Prasad, K Vinaya, CSA Kumar, S Swarup…

文献索引:Benaka Prasad; Vinaya; Ananda Kumar; Swarup, Sanjay; Rangappa Medicinal Chemistry Research, 2010 ,  vol. 19,  # 3  p. 220 - 235

全文:HTML全文

被引用次数: 5

摘要

Abstract A series of novel diphenyl (piperidin-4-yl) methanol derivatives 10 (a–n) were synthesized and characterized by 1 H NMR, LC/MS, FTIR, and elemental analyses. All the synthesized compounds were evaluated for cell proliferation by MTT assay. The antiproliferative effects of the synthesized compounds were tested against viable human skin fibroblast cell line and carcinoma cell lines, namely HeLa cells, HT-29 cells, MCF-7 ...