Metal-free regioselective oxidative biaryl coupling leading to head-to-tail bithiophenes: Reactivity switching, a concept based on the iodonium (III) intermediate
K Morimoto, N Yamaoka, C Ogawa, T Nakae…
文献索引：Kita, Yasuyuki; Morimoto, Koji; Ito, Motoki; Ogawa, Chieko; Goto, Akihiro; Dohi, Toshifumi Journal of the American Chemical Society, 2009 , vol. 131, # 5 p. 1668 - 1669
A new synthetic concept for obtaining unsymmetrical biaryl coupling products by an oxidative method is reported. Our synthetic strategy casts light on the reaction intermediate for switching the reactivity of 3-substituted thiophenes. On the basis of this strategy, a novel direct method for the synthesis of head-to-tail bithiophenes using hypervalent iodine (III) reagents has been developed.
