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Bimanes. 18.(Haloalkyl)-1, 5-diazabicyclo [3.3. O] octadienediones [halo-9, 10-dioxabimanes]: sulfur" extraction" by syn-(1-bromoethyl, methyl) bimane. Glutathione" …

…, EM Kosower, D Eisenberg, I Goldberg

文献索引:Radkowsky, Annette E.; Kosower, Edward M.; Eisenberg, Deborah; Godberg, Israel Journal of the American Chemical Society, 1986 , vol. 108, # 15 p. 4532 - 4541

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被引用次数: 5

摘要

Abstract: Glutathione (GSH) and the diastereomeric dibromides [syn-(1-bromoethyl, methyl) bimanes] derived from syn-(ethy1, methyl) bimane (4, 6-diethyl-3, 7-dimethyl-l, 5- diazabicyclo [3.3. O] octa-3, 6-diene-2, 8-dione) react to form a small amount of the (GS), derivative and substantial amounts of isomeric (cis-and trans-) thia-bridged bimanes [p-(S)- (methylmethylene, methyl) bimane]. The latter are accompanied by a new compound, ...