Synthetic communications

Preparation of N??chloroamides using trichloroisocyanuric acid

GA Hiegel, TJ Hogenauer, JC Lewis

文献索引：Hiegel, Gene A.; Hogenauer, Tyrone J.; Lewis, Justin C. Synthetic Communications, 2005 , vol. 35, # 15 p. 2099 - 2105

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被引用次数: 19

摘要

N??Chloramides can be an intermediate in the familiar Hoffmann degradation for the conversion of amides into amines containing one less carbon (Scheme 1).11. Shioiri , T. 1991. “The Hofmann reaction”. In Comprehensive Organic Synthesis Edited by: Trost , BM Vol. 6, 800–806. New York: Pergamon. ... View all references The N??chloroamides used in the Hoffmann degradation were often prepared utilizing a high concentration of hypochlorite solution, which was ...