Journal of fluorine chemistry

Reactions of ethyl bromodifluoroacetate in the presence of copper powder

K Sato, M Omote, A Ando, I Kumadaki

文献索引：Sato; Omote; Ando; Kumadaki Journal of Fluorine Chemistry, 2004 , vol. 125, # 4 p. 509 - 515

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被引用次数: 61

摘要

We have examined the reaction of ethyl bromodifluoroacetate (1) in the presence of copper powder as a procedure for the synthesis of compounds containing a CF2 group. The complex formed in the above reaction reacted with vinyl or aryl iodides to give cross- coupling products, with Michael acceptors to give 1, 4-addition products and with olefins to give radical addition products. The cross-coupling reaction was applied to the synthesis of ...