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Tetrahedron: Asymmetry

Diastereoselective synthesis of (2S, 5S)-and (2S, 5R)-N-benzyloxycarbonyl-5-hydroxypipecolic acids from trans-4-hydroxy-l-proline

JC Jung, MA Avery

文献索引:Tetrahedron Asymmetry, , vol. 17, # 17 p. 2479 - 2486

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被引用次数: 20

摘要

... Tetrahedron: Asymmetry. Volume 17, Issue 17, 2 October 2006, Pages 2479–2486. ... lactonization, accomplished by refluxing for 1 h in benzene with a catalytic amount of p-toluenesulfonic acid monohydrate (p-TsOH·H 2 O) to afford N-benzyloxycarbonyl lactone 17 in 90% yield ...