European Journal of Organic Chemistry

A Mild Titanium??Catalyzed Synthesis of Functionalized Amino Coumarins as Fluorescence Labels

L Wirtz, U Kazmaier

文献索引：Wirtz, Lisa; Kazmaier, Uli European Journal of Organic Chemistry, 2011 , # 35 p. 7062 - 7065

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被引用次数: 10

摘要

Abstract In contrast to Brønsted and other Lewis acids ClTi (OiPr) 3 is especially suited to catalyze the formation of amino-substituted coumarins from aminophenols and functionalized β-oxo esters in a Pechmann condensation. This straightforward protocol allows the synthesis of fluorescence labels and false fluorescent neurotransmitters.