Synthesis of phosphatidylcholine: an improved method without using the cadmium chloride complex of sn-glycero-3-phosphocholine

K Ichihara, H Iwasaki, K Ueda, R Takizawa…

文献索引：Ichihara, Ken'ichi; Iwasaki, Hitomi; Ueda, Kaori; Takizawa, Ryoko; Naito, Hideko; Tomosugi, Mitsuhiro Chemistry and Physics of Lipids, 2005 , vol. 137, # 1-2 p. 94 - 99

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被引用次数: 21

摘要

An improved safe method that does not contaminate the environment with cadmium chloride, a toxic heavy metal salt, was developed for the synthesis of phosphatidylcholine (PC). PC was synthesized from sn-glycero-3-phosphocholine (GPC) and fatty acid in one step under mild conditions without the use of cadmium chloride. GPC was prepared from egg yolk PC and adsorbed by kieselguhr in a Teflon vessel. The GPC on kieselguhr was ...