Efficacious and orally bioavailable thrombin inhibitors based on a 2, 5-thienylamidine at the P1 position: discovery of N-carboxymethyl-d-diphenylalanyl-l-prolyl [(5- …
K Lee, CW Park, WH Jung, HD Park…
文献索引：Journal of Medicinal Chemistry, , vol. 46, # 17 p. 3612 - 3622
... Journal of Medicinal Chemistry. ... prophylaxis of venous and arterial thrombosis. 1. Small-molecule inhibitors of thrombin have been of considerable interest to medicinal chemists over the past decade. 2 Some years ago, we ...
